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FDA Drug & Medical Device Recall News & Comments 
Thursday, November 13 2008

Diabetes Drug Avandia & PPH

Primary Pulmonary Hypertension (PPH) caused by Avandia? 

Primary Pulmonary Hypertension (PPH) also referred to as Primary Arterial Hypertension (PAH) are serious and aggressive heart and lung diseases that narrow the blood vessels in the lungs. This narrowing of the blood vessels leads to higher arterial blood pressure within the lung and heart. This increased pulmonary hypertension leads to serious heart and lung damage, heart failure, heart attacks and possible strokes. PPH has been linked to the use of the popular diet drugs known as Fen-Phen, Pondimin, Redux and to herbal nutritional supplements containing ephedra PPH (ma huang), St. John's Wort PPH and recently a possible link to the use of diabetes drug called Avandia PPH. Avandia distributed by GlaxoSmithKline. Avandia is used to treat patients with type 2 diabetes.

In 2007, the Food & Drug Administration (FDA) and GlaxoSmithKline issued a warning letter (Dear Dr. Letter) treating doctors of Avandia patients of a potential link between Avandia and the onset of Primary Pulmonary Hypertension. See Avandia side effects for more news about increased risks.

Posted by: DW AT 12:00 pm   |  Permalink   |  Email
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